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ROM: How does it compare to cortisone shots?

Cortisone, aka: corticosteroid or steroid shots, are widely used in orthopedics. These injections do not do anything to repair the tissue, they can merely cover the pain up, and have also been shown to have degenerative effects on the tissue (eg: leading to further arthritis). Regenerative orthopedic medicines actually work on the opposite end of the healing process, allowing for the good aspects of natural inflammation and healing to occur while not degenerating/breaking-down the tissue. Instead, it stabilizes and even potentially regenerates the tissue!

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